What to Expect in Your First Month

Your First Month on GLP-1 Therapy

Starting a new medication can feel uncertain. Here's a realistic timeline of what most patients experience.

Week 1–2: Adjustment Period

Your clinician will start you on a low dose. During this time:

• You may notice reduced appetite within the first few days
• Some patients experience mild nausea — this typically resolves
• Stay hydrated and eat smaller, more frequent meals

Week 3–4: Finding Your Rhythm

By the third week, most patients report:

• A noticeable decrease in cravings, especially for high-sugar foods
• Early weight changes (typically 2–5 lbs in the first month)
• Improved energy levels as eating patterns stabilize

Tips for Success

1. Track your meals — not for calories, but to notice changing preferences
2. Prioritize protein — it supports satiety and preserves muscle mass
3. Move daily — even 20 minutes of walking makes a measurable difference
4. Communicate with your clinician — dose adjustments are normal and expected

When to Contact Your Care Team

Reach out if you experience persistent nausea, severe abdominal pain, or no appetite reduction after two weeks. Your dosing may need adjustment.

Next, we'll discuss nutrition strategies that complement GLP-1 therapy.